3 Covid Shots Generate Good Response In Under-5s: Pfizer-BioNTech
Pfizer Covid vaccine: The announcement comes as the FDA is planning meetings in the coming weeks to weigh authorizing Covid vaccines.
Washington: The Pfizer-BioNTech Covid vaccine is safe and effective for children aged six months to under five years when given in three doses, the companies said in a statement Monday.
The announcement comes as the US Food and Drug Administration (FDA) is planning meetings in the coming weeks to weigh authorizing Covid vaccines among the youngest children, the only age group who are not yet eligible in most countries, a source of concern to many parents.
Pfizer-BioNTech evaluated three doses, given at three micrograms, in a clinical trial and found the vaccine evoked a strong immune response. Side effects were similar in the vaccine and placebo groups.
Vaccine efficacy was 80.3 percent, according to a preliminary estimate.
“We are pleased that our formulation for the youngest children, which we carefully selected to be one-tenth of the dose strength for adults, was well tolerated and produced a strong immune response,” said Pfizer CEO Albert Bourla in a statement.
“We look forward to soon completing our submissions to regulators globally with the hope of making this vaccine available to younger children as quickly as possible, subject to regulatory authorization,” he added.
The FDA has tentatively scheduled three dates in June where experts will meet and likely decide whether to authorize the Pfizer Covid vaccine for under-fives and the Moderna vaccine for under-sixes, which is given as two shots of 25 micrograms.
The agency was originally set to evaluate the Pfizer vaccine given as two doses in February, but data showed it did not provoke a strong enough immune response in children aged two to four. The FDA then asked to see data for a third shot.
Otofacial Syndrome Left Chicago’s Joseph Williams Without Jaw, He Refused To Give Up
Joseph Williams underwent a number of surgeries in Chicago, as doctors tried to construct a jaw but he said his body rejected it.
A man who was born without jaw and bullied his entire life has said that love saved his life after surviving decades of feeling “worthless”. Forty-one-year-old Joseph Williams from Chicago was quoted as saying by news.co.au that others struggling with challenges like him also deserve more out of life.
“Dating was also hard for me because I had such low self-esteem and felt worthless, but when I started believing in myself and realised I deserved more, I ended up finding my wife,” he told the publication.
Mr Williams was born with a rare congenital disorder called otofacial syndrome. It is caused by a mutated gene and left him unable to speak or eat with his mouth.
Due to the condition, Mr Williams uses sign language and consumes food through a tube.
“I can’t eat, speak or even breathe properly,” he said. “I have a tube in my stomach, which I can place blended food into, but this means that I have never tasted food.”
But these issues did not stop Mr Williams from living his life.
“I understand that I am different and that some people will think I am ugly and not accept me, but I am still a person who has a heart, feelings and a brain,” said the 41-year-old, who works as a welder. “I should be treated with respect, just as anyone else should be,” he added.
According to a report in the New York Post, when he was growing up, Mr Williams was constantly told about things he couldn’t do. “But I didn’t want my condition to hold me back and I didn’t want to be limited.”
Mr Williams underwent a number of surgeries in Chicago, as doctors tried to construct a jaw but he said his body rejected it.
-How An Energy Expert Triggered Vladimir Putin With One Word
US Shale Oil Gas: Daniel Yergin, the vice chairman of S&P Global, discussed the incident on the latest episode of the “What Goes Up” podcast.
Daniel Yergin was at the St. Petersburg International Economic Forum in 2013 when he got a daunting request: Could he pose the first question from the audience to Vladimir Putin?
“I started to ask a question, I mentioned the word ’shale,’” he recalls, referring to a once-unconventional source of oil and natural gas that by then was flowing freely in the U.S. due to advances in production techniques. “And he started shouting at me, saying shale’s barbaric.”
Yergin, the vice chairman of S&P Global, discussed the incident on the latest episode of the “What Goes Up” podcast, along with other insights from his book “The New Map: Energy, Climate, and the Clash of Nations.” US shale oil and gas have had a much bigger impact on geopolitics than people recognize, Yergin says. It has posed a threat to Putin in multiple ways, especially as US natural gas would compete with Russia’s in Europe.
Below are lightly edited and condensed highlights of the conversation.
Q: How did the US become a big oil and gas producer?
A: It was a revolution. We had eight presidents in a row, starting with Richard Nixon right up through Barack Obama, saying ‘We want to become energy independent.’ And it seemed a joke, it was never going to happen. But there was this technology called shale, which really involves hydraulic fracturing, as it’s called, combined with horizontal drilling. And there was one really obsessed individual — it’s so interesting, the role of obsessed individuals in economic change — named George P. Mitchell, who was convinced if you just worked somehow, even though the textbooks said it was impossible, you could make it work. And for 20 years, 25 years people scoffed, but then it did work. And even his own company, people were telling him not to spend money on it. But if he hadn’t spent that money, I’m not sure that we would’ve been where we were.
And then in the early 2000s, you started to see wildcatters — independents, as they’re called — small companies starting to adapt that technology. And then people said, ‘Oh, US natural gas supply, instead of going down is going up. And then they said, well, if it works for gas, maybe it works for oil too — in about 2008, 2009. So this all really happened in that period from about 2008, that’s when it all really began, the shale revolution. And it just took the US from an entirely different position. And if you had told people in 2002 that the US was going to be the world’s largest oil producer, larger than Russia, larger than Saudi Arabia, the world’s largest producer of natural gas, and this year, the world’s largest exporter of LNG, they would’ve said you’re living in a fantasy world.
Q: It occurred to me as I was reading your book that the US going from being renowned as the biggest consumer of energy in the world to now a major producer almost escalates the geopolitical tensions. Does it make America’s influence different in this environment?
A: That’s absolutely right. I deal with a lot of things from Ukraine to climate in the book, but I start with shale because shale’s really had a much bigger impact on geopolitics that people recognize. The story I tell in the book is when I was in St. Petersburg at a conference where Putin was speaking — 3,000 people there — I was told to ask the first question. I started to ask a question, I mentioned the word ’shale.’ And he started shouting at me saying shale’s barbaric. He knew that US shale was a threat to him in two ways. One, because it meant that US natural gas would compete with his natural gas in Europe, and that’s what we’re seeing today. And secondly, this would really augment America’s position in the world and give it a kind of flexibility it didn’t have when it was importing 60% of its oil.
The question started off innocuously. I was going to ask him a normal question about diversifying your economy. And I said ’shale,’ and to be shouted at by him in front of 3,000 people, a really unpleasant experience. The other person on the stage was chancellor Merkel, who was chancellor of Germany for 16 years. And you can see the enmity between the two. But Merkel’s now being criticized for policies like shutting down nuclear that led to Germany being more dependent on Russian gas. And the judgment of history is shifting a little bit.
Q: How did everyone get Russia so wrong?
A: Now there’s a kind of revisionism that the world shouldn’t have traded with Russia, shouldn’t have tried to integrate Russia into the world economy, particularly as Putin got more and more authoritarian. But, you say, well, what was the alternative? To leave it festering there? The best thing was to get it anchored in the world. Putin, he’s been in power now almost as long as Joseph Stalin. And I think he was becoming more and more authoritarian and people who have known him over the years said that Covid changed him. He was isolated for two years. He wasn’t meeting Western business people. He wasn’t meeting Western government officials and so forth. So I don’t think there was an alternative to not trying to integrate Russia into the world, but obviously what’s happening now is the world, at least the Western world, is slamming the door on Russia.
Q: Is Europe going to be able to just soldier on without succumbing to Russia and their demands when it starts getting colder again?
That’s the question that’s really weighing now because in terms of oil, there’s enough crude oil in the world. You have to move it around, but between strategic stocks, between demand being down in China, you can manage that. When you get into products like diesel, it gets harder. And then you’re going to the hardest thing with natural gas, and that is exactly as you go into the winter. So the big question now is can they fill storage so that they can get through the winter, and, by the way, not only stay warm, but keep industry operating. And I think we can say that Putin made a series of decisions which kind of were irrational — that his army was really good, that Ukraine wouldn’t be able to resist, that the US had just gone through getting out of Afghanistan and was deeply divided, that Europe was so dependent on his energy that they would say, ‘OK, this is terrible, but life goes on.’ And none of that happened. But I think he’s still calculating. And he said that ultimately this energy disruption — and we are in a huge disruption of energy markets — would be such a big threat to the European economy that the coalition that now exists would fall apart. I think that’s his wager right now. And the Achilles heel is what you pointed to: what happens as Europe goes into the fall and winter. And we’ve had at least one German, very prominent industrialist, who said, ‘This is too dangerous for the European economy. We should negotiate something with Putin.’
-Russia Claims It Fired Cruise Missiles To Destroy Ukrainian Weapons
Russia will head into the fourth month of its invasion of Ukraine on Tuesday with no end in sight to the fighting that has killed thousands.
Russia’s defence ministry on Monday said it had fired four Kalibr missiles from a submarine in the Black Sea to destroy the military equipment of a Ukrainian mountain assault brigade, the TASS news agency reported.
It was not immediately possible to verify the report.
Meanwhile, Russia will head into the fourth month of its invasion of Ukraine on Tuesday with no end in sight to the fighting that has killed thousands, uprooted millions and reduced cities to rubble.
After abandoning its assault on the capital, Kyiv, Russia is pressing on in the east and south in the face of mounting sanctions and a fierce Ukrainian counter-offensive bolstered by Western arms.
87 People were killed in a Russian air strike on the village of Desna last Tuesday, Ukrainian President Volodymyr Zelenskiy said on Monday during a speech to global business leaders at Davos.
Ukrainian authorities last week had said that eight people were killed in the strike on Desna, located in the northern Ukrainian region of Chernihiv.
-Over 6.5 Million People Left Ukraine Since War Began: UN Refugee Agency
Russia-Ukraine War: Since Russia’s invasion on Feb. 24, 6,538,998 refugees have left Ukraine, with the majority of them entering Poland.
Berlin: More than 6.5 million people have fled Ukraine since Russia’s invasion in late February, the U.N. refugee agency said.
Since Russia’s invasion on Feb. 24, 6,538,998 refugees have left Ukraine, with the majority of them entering Poland.
-Ukraine’s Zelensky Appeals For More Weapons In Davos Summit
Russia-Ukraine War: President Volodymyr Zelensky also urged to maximise sanctions against Moscow.
Davos: Ukrainian President Volodymyr Zelensky used the Davos summit on Monday to appeal for more weapons for his country and “maximum” sanctions against Moscow.
Speaking by videolink, Zelensky told the World Economic Forum that tens of thousands of lives would have been saved if Kyiv had received “100 percent of our needs at once back in February” when Russia invaded Ukraine.
“This is why Ukraine needs all the weapons that we ask (for), not just the ones that have been provided,” said Zelensky, flanked by Ukrainian flags and wearing an olive green T-shirt.
Zelensky called for an oil embargo on Russia, punitive measures against all its banks and the shunning of its IT sector, adding that all foreign companies should leave the country.
“There should not be any trade with Russia,” he told the gathering of the world’s political and business elites.
“I believe there are still no such sanctions against Russia — and there should be.”
While the United States, Britain and Canada have moved to ban Russian oil and gas, the European Union has been divided over imposing similar measures. EU members such as Germany and Hungary are heavily dependent on energy supplies from Russia.
The war in Ukraine is dominating the discussions in Davos, the first WEF meeting in more than two years. The Covid pandemic forced the cancellation of the 2021 in-person event and the postponement of this year’s confab until May.